Title: platelet-derived growth factor Long Title: IUPAC Gold Book - platelet-derived growth factor DOI: 10.1351/goldbook.13582 Status: current Definition Protein synthesized by platelets that is released into the serum during blood clotting. Note PDGF represents the major growth factor in human serum and is a potent mitogen for connective tissue and glial cells. Related Terms - mitogen: https://goldbook.iupac.org/terms/view/13461 - platelets: https://goldbook.iupac.org/terms/view/13580 Source - PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1231 (https://doi.org/10.1351/PAC-REC-11-06-03) Other Outputs - html: https://goldbook.iupac.org/terms/view/13582/html - json: https://goldbook.iupac.org/terms/view/13582/json - xml: https://goldbook.iupac.org/terms/view/13582/xml Citation: Citation: 'platelet-derived growth factor' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13582 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-05-10T22:59:58+00:00