Title: proteasome
Long Title: IUPAC Gold Book - proteasome
DOI: 10.1351/goldbook.13613
Status: current

Definition
Cytoplasmic and nuclear multiprotein proteolytic complex involved in degradation of excess, damaged, or misfolded proteins.

Note
Cytoplasmic proteasome is important in antigen processing and presentation by major histocompatibility complex (MHC) molecules.

Related Term
- major histocompatibility complex (MHC) molecules: https://goldbook.iupac.org/terms/view/13434

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1236 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13613/html
- json: https://goldbook.iupac.org/terms/view/13613/json
- xml: https://goldbook.iupac.org/terms/view/13613/xml

Citation: Citation: 'proteasome' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13613
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Accessed: 2026-07-23T21:58:44+00:00