Title: protein kinase C Long Title: IUPAC Gold Book - protein kinase C DOI: 10.1351/goldbook.13619 Status: current Definition Member of a kinase family with broad substrate specificity, activated by calcium, diacylglycerol, and (or) phorbol 12-myristate 13-acetate (PMA). Note It is activated during B-lymphocyte and T-lymphocyte activation. Related Terms - B-lymphocyte: https://goldbook.iupac.org/terms/view/12937 - T-lymphocyte: https://goldbook.iupac.org/terms/view/13724 - phorbol 12-myristate 13-acetate (PMA): https://goldbook.iupac.org/terms/view/13566 Source - PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1237 (https://doi.org/10.1351/PAC-REC-11-06-03) Other Outputs - html: https://goldbook.iupac.org/terms/view/13619/html - json: https://goldbook.iupac.org/terms/view/13619/json - xml: https://goldbook.iupac.org/terms/view/13619/xml Citation: Citation: 'protein kinase C' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13619 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-06-30T23:27:07+00:00