13660 IUPAC Gold Book - scleroderma 10.1351/goldbook.13660 13660 current mentioned: CREST syndrome 1 Chronic progressive autoimmune disease characterized by systemic fibrosis and vascular changes. There are two types: progressive systemic sclerosis, and a more limited and less rapidly progressive form known as CREST syndrome, referring to Calcinosis, Raynaud phenomenon, Esophageal dysfunction, Sclerodactyly, and Telangiectasias. Raynaud phenomenon https://goldbook.iupac.org/terms/view/13632 autoimmune disease https://goldbook.iupac.org/terms/view/12919 progressive systemic sclerosis https://goldbook.iupac.org/terms/view/13609 PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1242 (https://doi.org/10.1351/PAC-REC-11-06-03) https://goldbook.iupac.org/terms/view/13660/html https://goldbook.iupac.org/terms/view/13660/json https://goldbook.iupac.org/terms/view/13660/plain Citation: 'scleroderma' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13660 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-07-01T00:24:41+00:00