13663 IUPAC Gold Book - secondary lymphoid tissue 10.1351/goldbook.13663 13663 current synonym: secondary lymphoid organ 1 Tissue (organ) in which antigen-driven proliferation and differentiation of mature B and T lymphocytes take place following antigen recognition. Lymph nodes, Peyer’s patches, and the spleen. Lymph nodes https://goldbook.iupac.org/terms/view/13397 Peyer’s patches https://goldbook.iupac.org/terms/view/13559 T lymphocytes https://goldbook.iupac.org/terms/view/13724 mature B https://goldbook.iupac.org/terms/view/13448 mucosa-associated lymphoid tissue (MALT) https://goldbook.iupac.org/terms/view/13474 spleen https://goldbook.iupac.org/terms/view/13690 PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1242 (https://doi.org/10.1351/PAC-REC-11-06-03) https://goldbook.iupac.org/terms/view/13663/html https://goldbook.iupac.org/terms/view/13663/json https://goldbook.iupac.org/terms/view/13663/plain Citation: 'secondary lymphoid tissue' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13663 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-14T02:03:24+00:00