{"term":{"id":"13680","title":"Sjögren syndrome","longtitle":"IUPAC Gold Book - Sjögren syndrome","doi":"10.1351\/goldbook.13680","code":"13680","status":"current","definitions":[{"id":1,"text":"Chronic inflammation of the lachrymal and salivary glands, often accompanied by rheumatoid arthritis (RA) and the presence of autoantibodies in the blood, occurring chiefly among women.","notes":{"1":"Two types of Sjögren syndrome are distinguished: a primary (isolated) type and a secondary type associated with another underlying autoimmune disease [e.g., RA, systemic lupus erythematosus (SLE), systemic sclerosis (SSc), primary biliary cirrhosis (PBC), autoimmune hepatitis (AIH), multiple sclerosis, autoimmune thyroiditis, etc.]. Ro\/SS-A and La\/SS-B autoantibodies are used as classification criteria."},"links":[{"term":"autoantibodies","url":"https:\/\/goldbook.iupac.org\/terms\/view\/12913"},{"term":"autoimmune hepatitis (AIH)","url":"https:\/\/goldbook.iupac.org\/terms\/view\/12921"},{"term":"autoimmune thyroiditis","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13741"},{"term":"primary biliary cirrhosis (PBC)","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13600"},{"term":"rheumatoid arthritis (RA)","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13651"},{"term":"systemic lupus erythematosus (SLE)","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13710"}],"sources":["PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1245 (https:\/\/doi.org\/10.1351\/PAC-REC-11-06-03)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/13680\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/13680\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/13680\/plain"},"citation":"Citation: 'Sjögren syndrome' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.13680","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-06-30T06:10:56+00:00"}}