Title: thyroid-stimulating hormone receptor
Long Title: IUPAC Gold Book - thyroid-stimulating hormone receptor
DOI: 10.1351/goldbook.13742
Status: current

Definition
Main autoantigenic target in patients with Graves disease.

Note
Most TSHR autoantibodies are stimulatory, acting as agonists of thyroid-stimulating hormone, but receptor-blocking antibodies are also found.

Related Terms
- Graves disease: https://goldbook.iupac.org/terms/view/13187
- autoantibodies: https://goldbook.iupac.org/terms/view/12913
- autoantigenic: https://goldbook.iupac.org/terms/view/12914

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1253 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13742/html
- json: https://goldbook.iupac.org/terms/view/13742/json
- xml: https://goldbook.iupac.org/terms/view/13742/xml

Citation: Citation: 'thyroid-stimulating hormone receptor' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13742
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Accessed: 2026-05-10T14:53:22+00:00