Title: toxic epidermal necrolysis
Long Title: IUPAC Gold Book - toxic epidermal necrolysis
DOI: 10.1351/goldbook.13748
Status: current

Definition
A severe form of Stevens–Johnson syndrome with extensive detachment of the skin, often as a result of an allergic adverse drug reaction.

Related Terms
- Stevens–Johnson syndrome: https://goldbook.iupac.org/terms/view/13696
- adverse drug reaction: https://goldbook.iupac.org/terms/view/12851
- allergic: https://goldbook.iupac.org/terms/view/12858

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1254 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13748/html
- json: https://goldbook.iupac.org/terms/view/13748/json
- xml: https://goldbook.iupac.org/terms/view/13748/xml

Citation: Citation: 'toxic epidermal necrolysis' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13748
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-07-27T05:36:01+00:00