<?xml version="1.0" encoding="UTF-8"?>
<term>
  <id>13758</id>
  <title>tuberculin test</title>
  <longtitle>IUPAC Gold Book - tuberculin test</longtitle>
  <doi>10.1351/goldbook.13758</doi>
  <code>13758</code>
  <status>current</status>
  <synonym><em>synonym</em>: Mantoux test</synonym>
  <definitions>
    <item>
      <id>1</id>
      <text>Diagnostic test in which antigens derived from the organism causing tuberculosis (Mycobacterium tuberculosis) are injected subcutaneously; individuals who have been exposed to the organism develop a delayed-type hypersensitivity (DTH) response at the injection site \(\pu{24}\) to \(\pu{48 h}\) later.</text>
      <notes>
        <item>Those who have been previously vaccinated with bacille Calmette–Guérin (BCG) also show a positive response.</item>
      </notes>
      <links>
        <item>
          <term>bacille Calmette–Guérin (BCG)</term>
          <url>https://goldbook.iupac.org/terms/view/12940</url>
        </item>
        <item>
          <term>delayed-type hypersensitivity (DTH)</term>
          <url>https://goldbook.iupac.org/terms/view/13085</url>
        </item>
      </links>
      <sources>
        <item>PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1256 (https://doi.org/10.1351/PAC-REC-11-06-03)</item>
      </sources>
    </item>
  </definitions>
  <altoutputs>
    <html>https://goldbook.iupac.org/terms/view/13758/html</html>
    <json>https://goldbook.iupac.org/terms/view/13758/json</json>
    <plain>https://goldbook.iupac.org/terms/view/13758/plain</plain>
  </altoutputs>
  <citation>Citation: 'tuberculin test' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13758</citation>
  <license>The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.</license>
  <collection>If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .</collection>
  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-05-14T11:46:52+00:00</accessed>
</term>
