tyrosine kinase

synonym: protein tyrosine kinase
https://doi.org/10.1351/goldbook.13766
Any member of a family of enzymes that phosphorylates target proteins on tyrosine residues, thus playing a crucial role in signal transduction.
Note: Tyrosine kinases play a key role in lymphocyte activation. Major tyrosine kinases involved in T lymphocyte activation are Lck, Fyn, and ZAP-70; those involved in B lymphocyte activation are Blk, Fyn, Lyn, and Syk.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1257 [Terms] [Paper]
Citation: 'tyrosine kinase' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13766 RIS BibTex EndNote
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