hit threshold

https://doi.org/10.1351/goldbook.14145
Minimum activity that defines actives in a primary screen.
Notes:
  1. It is usually expressed as percentage of inhibition or stimulation relative to assay controls.
  2. A widely used hit threshold is \(\pu{50\%}\) inhibition. A more statistically meaningful and equally common threshold is three standard deviations from the mean.
Source:
PAC, 2011, 83, 1129. (Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)) on page 1143 [Terms] [Paper]
Citation: 'hit threshold' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.14145 RIS BibTex EndNote
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