15154 IUPAC Gold Book - bioequivalence 10.1351/goldbook.15154 15154 current 1 Relationship between two preparations of the same drug in the same dosage form that have a similar bioavailability. Dosage forms containing the same drug are said to be bioequivalent if they do not differ significantly in the bioavailability (e.g., AUC, \(c_{\rm{max}}\), \(t_{\rm{max}}\)) of the active constituent/ingredient, when administered in the same dose under similar experimental conditions. PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 977 (https://doi.org/10.1351/PAC-REC-04-10-14) https://goldbook.iupac.org/terms/view/15154/html https://goldbook.iupac.org/terms/view/15154/json https://goldbook.iupac.org/terms/view/15154/plain Citation: 'bioequivalence' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15154 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-06-28T15:42:51+00:00