https://doi.org/10.1351/goldbook.15194
Process in which powder particles are made to aggregate to larger particles called granules.
Notes:
- In the majority of cases, granulation is required in the production of tablets or capsules, when granules are made as an intermediate product.
- Granulation is preceded by mixing the necessary powdered ingredients to assure their uniform distribution in the granules.
- Granulation may be carried out by two methods: wet granulations which utilize nontoxic volatile liquids, like water or low alcohols; or dry methods in which high pressure is applied.