loading dose

https://doi.org/10.1351/goldbook.15203
Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Note: The objective is to reach quickly the therapeutically beneficial plasma level. This is followed by smaller (maintenance) doses in order to maintain the plasma concentration.
Source:
PAC, 2009, 81, 971. (Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)) on page 989 [Terms] [Paper]
Citation: 'loading dose' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.15203 RIS BibTex EndNote
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