15714 IUPAC Gold Book - fixed dose procedure 10.1351/goldbook.15714 15714 current 1 Acute toxicity test in which a substance is tested initially at a small number (3 or 4) predefined doses to identify which produces evident toxicity without lethality: The test may be repeated at one or more higher or lower defined discriminating doses to satisfy the criteria. PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1224 (https://doi.org/10.1351/pac200779071153) https://goldbook.iupac.org/terms/view/15714/html https://goldbook.iupac.org/terms/view/15714/json https://goldbook.iupac.org/terms/view/15714/plain Citation: 'fixed dose procedure' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15714 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-09T21:45:29+00:00