15918 IUPAC Gold Book - nitrosative stress 10.1351/goldbook.15918 15918 current 1 Adverse effects occurring when the generation of reactive nitrogen species in a system exceeds the system’s ability to neutralize and eliminate them; nitrosative stress may lead to nitrosylation reactions that can alter protein structure, thus inhibiting normal function. PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1270 (https://doi.org/10.1351/pac200779071153) https://goldbook.iupac.org/terms/view/15918/html https://goldbook.iupac.org/terms/view/15918/json https://goldbook.iupac.org/terms/view/15918/plain Citation: 'nitrosative stress' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15918 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-23T22:00:47+00:00