05990 IUPAC Gold Book - stereoselective synthesis 10.1351/goldbook.S05990 S05990 current 1 A chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereoisomeric) products in unequal amounts. Traditionally called asymmetric synthesis. asymmetric synthesis https://goldbook.iupac.org/terms/view/A00484 chirality https://goldbook.iupac.org/terms/view/C01058 sequence https://goldbook.iupac.org/terms/view/ST06775 stereoselectivity https://goldbook.iupac.org/terms/view/S05991 PAC, 1996, 68, 2193. 'Basic terminology of stereochemistry (IUPAC Recommendations 1996)' on page 2219 (https://doi.org/10.1351/pac199668122193) https://goldbook.iupac.org/terms/view/S05990/html https://goldbook.iupac.org/terms/view/S05990/json https://goldbook.iupac.org/terms/view/S05990/plain Citation: 'stereoselective synthesis' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.S05990 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-06-28T23:53:13+00:00