https://doi.org/10.1351/goldbook.12876
Swelling that occurs in the tissue just below the surface of the skin, most often around the lips and eyes, the mucous membranes and occasionally the viscera.
Notes:
- It may be genetic, when it is referred to as hereditary angioedema (HAE), but is more usually caused by an allergic reaction to either food or medication, and is then called acquired angioedema (AAE).
- Angioedema may take from minutes to hours to develop. Severe angioedema can compromise the airway, and can be life-threatening.
- Angioedema is often associated with dermatographism, urticaria, erythema, and purpura. It may sometimes be a sign of a condition such as leukemia or Hodgkin disease.
- Angioedema is similar to hives, but hives involve itchy red welts on the surface of the skin, whereas angioedema is a deeper swelling under the skin.