constant region

synonyms: C region, constant (C) region
https://doi.org/10.1351/goldbook.13039
Part of an immunoglobulin (Ig) or T-cell receptor (TCR) that is relatively constant in amino acid sequence among different Ig or TCR molecules.
Note: In an antibody molecule the constant regions of each chain are composed of up to four C domains. The constant region of an antibody determines its general type of interaction.
See also: variable (V) region
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1148 [Terms] [Paper]
Citation: 'constant region' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13039 RIS BibTex EndNote
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