initialisms: CTL, TC
synonyms: CD8+ T cell, cytolytic T cell, cytotoxic T cell, killer T cell
https://doi.org/10.1351/goldbook.13072
Any of a subset of T lymphocytes bearing the CD8 surface marker and able to kill target cells [infected somatic or tumor cells, recognized by the antigen receptor complex (TCR/CD3)] after induction of a specific immune response to the antigens bound to major histocompatibility complex (MHC) class I molecules.
Note: CD4+ T cells may also become cytotoxic.