cytotoxic T lymphocyte antigen 4

initialism: CTLA-4
synonym: CD152
https://doi.org/10.1351/goldbook.13073
High affinity receptor for B7 molecules expressed on T cells, binding of which inhibits T cell activation.
Note: Mutations in the gene encoding CTLA-4 have been associated with various autoimmune diseases.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1154 [Terms] [Paper]
Citation: 'cytotoxic T lymphocyte antigen 4' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13073 RIS BibTex EndNote
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