Fc fragment

synonym: Fc region
https://doi.org/10.1351/goldbook.13137
Crystallizable, non-antigen-binding fragment of an immunoglobulin (Ig) molecule obtained following papain digestion. Consists of the C-terminal portion of both heavy chains, responsible for binding to Fc receptors and complement factor C1q.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1164 [Terms] [Paper]
Citation: 'Fc fragment' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13137 RIS BibTex EndNote
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