heavy chain

synonym: H-chain
https://doi.org/10.1351/goldbook.13198
Larger of the two types of polypeptide chain found in immunoglobulin (Ig) molecules.
Note: Each heavy chain is linked by disulfide bonds to a light chain and to another, identical heavy chain. Each heavy chain consists of an Fc fragment and an Fd fragment. Heavy chains carry the antigenic determinants that differentiate the various immunoglobulin classes.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1173 [Terms] [Paper]
Citation: 'heavy chain' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13198 RIS BibTex EndNote
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