hypervariable region

https://doi.org/10.1351/goldbook.13245
Amino acid sequence within the immunoglobulin (Ig) and T-cell receptor (TCR) variable (V) regions that shows the greatest variability and contributes most to the antigen or peptide-major histocompatibility complex (MHC) molecule binding site.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1180 [Terms] [Paper]