positive assay control

synonym: high control
https://doi.org/10.1351/goldbook.14182
Experimental conditions designed to produce the signal reflective of maximum biological effect in an assay.
Note: For a binding or an activation mechanism, it is typically the signal measured in the presence of a test compound. For an inhibitory or antagonist mechanism, it is the minimum signal, obtained in the absence of the reference inhibitor.
Source:
PAC, 2011, 83, 1129. (Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)) on page 1151 [Terms] [Paper]
Citation: 'positive assay control' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.14182 RIS BibTex EndNote
Div. VIITextXMLJSON