dominant lethal mutation

https://doi.org/10.1351/goldbook.15651
Genetic change occurring in a germ cell that does not cause dysfunction of the gamete but which is lethal to the fertilized egg or developing embryo which develops from it.
Note: Induction of a dominant lethal event after exposure to a chemical substance (dominant lethal test) indicates that the substance has affected germinal tissue of the test species.
Source:
PAC, 2007, 79, 1153. (Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)) on page 1208 [Terms] [Paper]
Citation: 'dominant lethal mutation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.15651 RIS BibTex EndNote
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