drug safety

https://doi.org/10.1351/goldbook.12649
Assessment of the nontolerable biological effects of a drug.
Note: Because the nontolerable effects of a drug are directly related to its concentration or dose, safety is generally ranked relative to the dose required to obtain the desirable effect.
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1733 [Terms] [Paper]