gene rearrangement

https://doi.org/10.1351/goldbook.13169
Structural alteration in a chromosome that changes the order of its genetic loci, occurring by DNA recombination, e.g., during development or in some cancers.
Note: In immunology, it refers to recombination of gene segments in immunoglobulin (Ig) and T-cell receptor (TCR) loci to produce a functional variable (V) region sequence.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1169 [Terms] [Paper]
Citation: 'gene rearrangement' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13169 RIS BibTex EndNote
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