https://doi.org/10.1351/goldbook.13660
Chronic progressive autoimmune disease characterized by systemic fibrosis and vascular changes.
Note: There are two types: progressive systemic sclerosis, and a more limited and less rapidly progressive form known as CREST syndrome, referring to Calcinosis, Raynaud phenomenon, Esophageal dysfunction, Sclerodactyly, and Telangiectasias.